Clostridium difficile-associated colitis after neomycin treated with metronidazole.

The cause of uraemic pruritus is unknown.In some cases it may be due to secondary hyperparathyroidism.Only in these patients is parathyroidectomy indicated.2The mechanisms of other treatments such as ultraviolet light3 or cholestyramine4 are unknown and are effective in only some cases.In our patient the rapid and complete disappearance of pruritus after lowering the dialysate magnesium concentration suggests a causative relation between itching and serum magnesium concentration.Lowering the dialysate magnesium concentration is known to restore nerve conduction velocity towards normal in patients receiving CHD,5 and this could be the reason for the complete disappearance of the pruritus in our patient.