Key result
Age 75 or older is linked to serious complications including mortality and restenosis after CAS.
Why the study?
The study aimed to evaluate risk factors for complications after carotid artery stenting with cerebral protection in patients with severe carotid stenosis.
What are the risk factors for complications following carotid artery stenting with cerebral protection in patients with severe carotid stenosis?
Observational (n=95)
No
What are the risk factors for complications following carotid artery stenting with cerebral protection in patients with severe carotid stenosis?
p-value: p=0.040
In patients undergoing carotid artery stenting with cerebral protection, age over 75 years is a significant risk factor for serious complications including TIA and mortality.
Supports heightened caution for carotid stenting patients aged ≥75; leaves open whether age should guide selection pending prospective validation.
Purpose: The aim of the study was to evaluate the risk factors for CAS with cerebral protection and the incidence of complication in patients with severe carotid stenosis. Materials and Methods: Overall, 95 consecutive patients with an average age of 64.67 years (28 - 83) (16 women (17%) and 79 men (83%)) were enrolled in the prospective monocentric study. Indication for CAS was symptomatic carotid stenosis ≥70% (n = 60 (63.16%)) or asymptomatic stenosis ≥80% (n = 35 (36.84%)) according to the NASCET criteria on DSA, which were not suitable for surgery. Results: From the selected risk factors, the most frequently found were arterial hypertension in 87 patients (91.6%), ischemic heart disease in 70 (73.7%), hyperlipidemia in 61 (64.2%), history of stroke in 43 (45.3%), diabetes mellitus in 35 (36.8%), smoking in 13 (13.7%), and age more than 75 years in 9 (9.5%). Significantly more frequent complications in elderly patients (more than the age of 75 years) were experienced: TIA (p = 0.049), early death (p = 0.049), restenosis (p = 0.04), and overall mortality (p = 0.04). Conclusion: Among the studied risk factors, only patients more than the age of 75 years were affected by the incidence of serious complications.
No takes yet. Share an insight, caveat, or question.
Zeleňák et al. (2013) conducted an observational in Severe carotid stenosis (n=95). Age ≥ 75 years (during carotid artery stenting) vs. Age < 75 years was evaluated on Overall mortality (p=0.040).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: