What question did this study set out to answer?

To review the surgical outcomes of transthoracic esophagectomy and left thoracotomy in early esophageal squamous cell carcinoma (ESCC), and to identify determinants of lymph node metastasis and overall survival.

June 30, 2013Asian Pacific Journal of Cancer PreventionOpen Access

Surgical Treatment for Early Esophageal Squamous Cell Carcinoma

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To review the surgical outcomes of transthoracic esophagectomy and left thoracotomy in early esophageal squamous cell carcinoma (ESCC), and to identify determinants of lymph node metastasis and overall survival.
Reviewed clinicopathological records of 228 patients with early ESCC (152 males, 76 females; median age 55 years) who underwent transthoracic esophagectomy with lymphadenectomy without preoperative adjuvant therapy.
Selected patients underwent either a left thoracotomy (n=208) or a right thoracotomy (n=20, reserved for upper mediastinal lymph nodes >5 mm on CT).
Employed chi-square or Fisher's exact tests to identify factors related to lymph node metastasis, alongside univariate and multivariate analyses to determine prognostic factors.
Lymph node metastasis occurred in 0% (0/18) of carcinoma in situ, 1.6% (1/62) of mucosal tumors, and 18.2% (27/148) of submucosal tumors.
The 5- and 10-year overall survival rates were 81.4% and 70.1%, respectively, with upper mediastinal lymph node metastases observed in only 7 patients during follow-up.
Histologic grade (P=0.026) and pT category (P=0.008) were the only significant independent prognostic factors for survival on multivariate analysis.

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Implication

Retrospective study shows high survival after surgical resection in early esophageal squamous cell carcinoma, indicating left thoracotomy is acceptable for selected patients.

Cite This Study

Chen et al. (2013) studied this question.

synapsesocial.com/papers/6aa9243ff8a0f247772636a1 https://doi.org/10.7314/apjcp.2013.14.6.3825

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Implication

Retrospective study shows high survival after surgical resection in early esophageal squamous cell carcinoma, indicating left thoracotomy is acceptable for selected patients.

Surgical Treatment for Early Esophageal Squamous Cell Carcinoma

Key Points

Discussion

Implication

Cite This Study

Surgical Treatment for Early Esophageal Squamous Cell Carcinoma

Key Points

Discussion

Implication

Cite This Study

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