What question did this study set out to answer?

This study evaluates the characteristics and risk factors of lymph node metastasis in early esophageal squamous cell carcinoma.

Characteristics of Lymph Node Metastasis in Esophageal Squamous-Cell Carcinoma Undergoing Upfront Minimally Invasive Esophagectomy: A Prospective Surgical Cohort Study

View Full Paper

Ask AI

Bookmark

Authors

Prospective surgical cohort study evaluates lymph node metastasis in early esophageal squamous cell carcinoma, suggesting significant risk factors.

This study evaluates the characteristics and risk factors of lymph node metastasis in early esophageal squamous cell carcinoma.
Prospective cohort study conducted from October 2022 to May 2024.
Patients with early esophageal squamous cell carcinoma undergoing minimally invasive esophagectomy and extended lymph node dissection were included.
Univariate and multivariable logistic regression analyses were performed to identify associated risk factors for lymph node metastasis.
Overall rate of lymph node metastasis was 30%, with increased incidence by pathological T stage: 14.3% (pT1a), 32.1% (pT1b), and 50% (pT2).
Tumor size >2 cm was independently associated with lymph node metastasis (OR 5.47; 95% CI: 1.05-32.65; p = 0.04).
Patients without lymph node metastasis had significantly longer disease-free survival (22.4 months) compared to those with lymph node metastasis (14.5 months; p = 0.003).

Pham et al. (2026) studied this question.

View Full Paper

Ask AI

Bookmark

Prospective surgical cohort study evaluates lymph node metastasis in early esophageal squamous cell carcinoma, suggesting significant risk factors.