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August 1, 1984Survey of Anesthesiology

Servo-Controlled Closed-Circuit Anaesthesia. A Method for the Automatic Control of Anaesthesia Produced by a Volatile Agent in Oxygen

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Key result

Servo-controlled closed-circuit anesthesia accurately estimates uptake and controls end-tidal halothane concentration to within ~0.1%.

  • n=12

Why the study?

A method for automatic control of anaesthesia using a volatile agent in oxygen was developed to improve maintenance of end-tidal anaesthetic concentrations.

Does a servo-controlled closed-circuit anaesthesia system accurately control end-tidal concentration of volatile anaesthetic agents in clinical subjects?

Population

12 clinical subjects and laboratory testing

Comparison

Servo-controlled closed-circuit anaesthesia vs manual control

Design

Other study type with closed-loop servo system testing

Authors

JRJ. A. S. RossRWR.T. WLOCHDWDavid WhiteAmerican Society of Nephrology

Discussion

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Implication

May enable automated volatile delivery systems; leaves open whether precision improves safety or outcomes in practice.

Structured PICO

Does a servo-controlled closed-circuit anaesthesia system accurately control end-tidal concentration of volatile anaesthetic agents in clinical subjects?

P
Population
12 subjects undergoing clinical testing of a servo-controlled closed-circuit anaesthesia system.
I
Intervention
Servo-controlled closed-circuit anaesthesia using a closed-loop servo system with direct liquid injection
O
Outcome
Accuracy of end-tidal anaesthetic concentration control and estimation of anaesthetic uptakesurrogate

A servo-controlled closed-circuit anaesthesia system can accurately maintain end-tidal volatile anaesthetic concentrations to within 0.1%.

Limitations

  • Zero offset in the Engstrom EMMA caused by humidity
  • Intrinsic characteristic of the simple proportional controller used

Cite This Study

Ross et al. (1984) studied Anaesthesia (n=12). Servo-controlled closed-circuit anaesthesia was evaluated on End-tidal halothane concentration control. A servo-controlled closed-circuit anaesthesia system accurately estimated anaesthetic uptake and controlled end-tidal halothane concentration to within 0.1%.

synapsesocial.com/papers/6aa929fb11a60bccbd263a1dhttps://doi.org/10.1097/00132586-198408000-00046
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Also Consider

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  1. 1Closed-Loop Anesthesia: Advances in Automated Drug Delivery and Perioperative Monitoring2026 · 1 citations
  2. 2Closed-Loop Propofol Administration2015 · 13 citations
  3. 3End-Tidal Control Versus Manual Control of Inhalational Anesthesia Delivery: A Randomized Controlled Noninferiority Trial2024 · 9 citations
  4. 4Progress of automatic drug delivery in anaesthesia—The ‘Rostock assistant system for anaesthesia control (RAN)’2008 · 25 citations
  5. 5Closed-loop Administration of General Anaesthesia: From Sensor to Medical Device2017 · 6 citations