Key result
Neurosarcoidosis-induced central hypothermia can present with Osborn waves and associated findings on ECG.
Why the study?
While clinical scenarios of environmental and iatrogenic hypothermia inducing Osborn waves have been described, the exact conditions required to induce such waves have been debated.
Case Report (n=1)
This case highlights neurosarcoidosis-induced central hypothermia as a novel etiology for the development of Osborn waves on ECG.
Neurosarcoidosis may cause Osborn waves via central hypothermia; extends the differential but remains hypothesis-generating.
Osborn waves, or J waves, initially described by John Osborn in 1953 in hypothermic dog experiments, are highly sensitive and specific for hypothermia. Initially thought to be secondary to a hypothermia-induced “injury current,” they have more recently been attributed to a voltage differential between epicardial and endocardial potassium (Ito) currents. While the exact conditions required to induce such waves have been debated, numerous clinical scenarios of environmental and iatrogenic hypothermia have been described. Below, we report a novel case of hypothermia—that of neurosarcoidosis-induced central hypothermia with resultant Osborn waves and other associated findings found on electrocardiogram (ECG).
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Troutman et al. (2019) conducted a case report in Neurosarcoidosis-induced central hypothermia (n=1). Neurosarcoidosis-induced central hypothermia was evaluated on Osborn waves and associated findings on ECG. Neurosarcoidosis-induced central hypothermia can present with Osborn waves and other associated findings on electrocardiogram.
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