Key result
Transfer to combined PD and HD is linked to better survival versus direct HD transfer.
Why the study?
Combined therapy with peritoneal dialysis and hemodialysis is widespread in Japan, but its clinical utility had been reported only in retrospective or before-and-after studies lacking a control group.
Does transfer to combined therapy with PD and HD improve survival compared to direct transfer to HD in incident PD patients?
Population
176 incident PD patients in Japan
Comparison
Transfer to combined therapy vs direct transfer to HD
Design
Prospective multicenter observational cohort study
Follow-up
Median 41 months
Authors
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Should not yet change transfer practices after PD failure; leaves open whether combined PD-HD improves survival in larger cohorts.
Cohort (n=176)
Yes
Does transfer to combined therapy with PD and HD improve survival compared to direct transfer to HD in incident PD patients?
Transfer to combined PD and HD therapy is clinically feasible and may offer survival benefits over direct transfer to HD, though larger studies are needed to confirm this.
Maruyama et al. (2022) conducted a cohort in Peritoneal dialysis (n=176). Transfer to combined therapy with peritoneal dialysis and hemodialysis vs. Transfer directly to hemodialysis was evaluated on Patient survival. Transfer to combined therapy with peritoneal dialysis and hemodialysis was associated with significantly better survival than direct transfer to hemodialysis, though limited by low event rates.
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