Key result
Infants under three with Ewing sarcoma show a 56% overall survival rate, matching older children.
Why the study?
Ewing sarcoma of bone in infants and toddlers younger than 3 years is rare and represents a distinct clinical subgroup within the Intergroup Ewing's Sarcoma Study population.
Observational (n=19)
Yes
Ewing sarcoma can occur in infants and toddlers, presenting with similar survival rates to older children but with a higher female predominance and risk of late therapy complications.
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Similar survival in infants with Ewing sarcoma extends data to this age group; prospective studies needed to optimize regimens and limit late effects.
Maygarden et al. (1993) conducted an observational in Ewing sarcoma of bone (n=19). Young age (<3 years) vs. Older children in the general IESS patient population was evaluated on Overall survival rate. Infants and toddlers younger than 3 years with Ewing sarcoma of bone had an overall survival rate of 56%, which was almost identical to the survival rates of older children.
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