Smoking as an independent risk factor for myocardial infarction or stroke in type 2 diabetes: a report from the Swedish National Diabetes Register
Key result
Smoking is linked to ~70% higher risk of first-incident MI in type 2 diabetes.
- HR 1.7
- 95% CI 1.4-2.0
- P<0.001
- n=13,087
Why the study?
Few earlier studies have analysed smoking as a risk factor for myocardial infarction or stroke in type 2 diabetic patients.
Does smoking increase the risk of myocardial infarction, stroke, and total mortality in patients with type 2 diabetes?
Population
13,087 female and male patients with type 2 diabetes aged 30-74 years from the Swedish National Diabetes Register
Comparison
Smoking vs non-smoking
Design
Longitudinal cohort study
Follow-up
Mean 5.7 years
Authors
Discussion
Loading...
Member takes
Implication
Smoking cessation efforts may be prioritized in type 2 diabetes; leaves open causal effects and extension to stroke or mortality.
Study Design
Type
Cohort (n=13,087)
Multicenter
Yes
Structured PICO
Does smoking increase the risk of myocardial infarction, stroke, and total mortality in patients with type 2 diabetes?
P
Population
13,087 patients with type 2 diabetes, aged 30-74 years and free of prior MI or stroke, followed for a mean of 5.7 years.
E
Exposure
Smoking
C
Comparator
Non-smoking
O
Outcome
First-incident fatal/nonfatal myocardial infarction (MI), stroke, and total mortalityhard clinical
Main Result
Hazard Ratio: 1.7 (95% CI 1.4–2)
p-value: p=<0.001
Smoking is a strong independent risk factor for myocardial infarction, stroke, and total mortality in patients with type 2 diabetes, particularly in middle-aged individuals.
Cite This Study
Nilsson et al. (2009) conducted a cohort in Type 2 diabetes (n=13,087). Smoking vs. Non-smoking was evaluated on First-incident fatal/nonfatal MI (HR 1.7, 95% CI 1.4-2.0, p=<0.001). Smoking was associated with a significantly increased risk of first-incident fatal/nonfatal MI in patients with type 2 diabetes (HR 1.7; 95% CI 1.4-2.0; P<0.001).