Key result
Smoking among patients with type 2 diabetes was associated with a significantly higher risk of all-cause mortality compared to non-smoking individuals without diabetes (HR 3.76 in men, HR 4.51 in women).
Why the study?
Does smoking increase the risk of coronary heart disease incidence and mortality, and all-cause mortality in people with and without type 2 diabetes?
Cohort (n=59,412)
Does smoking increase the risk of coronary heart disease incidence and mortality, and all-cause mortality in people with and without type 2 diabetes?
Hazard Ratio: 3.76 (95% CI 2.95–4.78)
Absolute Event Rate: 3.97% vs 0.88%
Smoking significantly amplifies the already high risk of coronary heart disease incidence and all-cause mortality in patients with type 2 diabetes, underscoring the critical need for smoking cessation in this population.
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Smoking may amplify mortality risk in T2D; extends observational data but leaves open causal effects and cessation benefits.
Barengo et al. (2017) conducted a cohort in Type 2 Diabetes (n=59,412). Smoking vs. Non-smoking (non-diabetic) was evaluated on All-cause mortality in men (diabetic smokers vs non-diabetic non-smokers) (HR 3.76, 95% CI 2.95-4.78). Smoking among patients with type 2 diabetes was associated with a significantly higher risk of all-cause mortality compared to non-smoking individuals without diabetes (HR 3.76 in men, HR 4.51 in women).
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