Key result
Over 8 hours of sedentary time linked to ~38% higher CKM syndrome risk among healthcare workers.
Why the study?
To determine the prevalence of Cardiovascular-Kidney-Metabolic syndrome and identify occupational, lifestyle, clinical, and female-specific risk factors among healthcare workers in China.
Cross-Sectional (n=1,110)
No
Cardiovascular-Kidney-Metabolic (CKM) syndrome is highly prevalent among Chinese healthcare workers, with BMI and sedentary time identified as key modifiable risk factors.
Sedentary time >8 h was associated with higher CKM syndrome risk in healthcare workers; hypothesis-generating and requires prospective studies before informing practice.
Objective: To determine the prevalence of Cardiovascular-Kidney-Metabolic (CKM) Syndrome and identify risk factors, including occupational factors, lifestyle factors and clinical measurements, and female-specific risk enhancers among healthcare workers in China. Methods: A cross-sectional study was conducted among healthcare workers at Taizhou People’s Hospital between April and May 2024. We collected data through surveys and laboratory results. Univariate and multivariate logistic regression analyses were performed to identify predictors of CKM syndrome and female-specific risk enhancers. Results: A total of 1110 participants were recruited (197 male; 913 female; mean age 34.8± 7.9). Almost 90% of male healthcare workers and 60% of female healthcare workers met the criteria for CKM syndrome (stage 1 or higher). Additionally, most male CKM syndrome patients were in stages 2– 3 (53.81%), while most female CKM syndrome patients were in stage 1 (35.82%). Multivariate logistic regression analysis revealed that, compared to those with over 20 years of work duration, a work duration of less than 10 years was a protective factor for CKM Syndrome. Additionally, more than 8 hours of sedentary time was identified as a risk factor compared to less than 2 hours (OR = 1.376, 95% CI 1.027– 1.844, P < 0.05). Receiver operating characteristic analysis showed that body mass index (BMI) was superior to fasting plasma glucose, glycated hemoglobin, triglycerides, and the triglyceride glucose product index in predicting CKM Syndrome, with area under the curve values of 0.884 vs 0.638, 0.708, 0.745, and 0.761, respectively ( P < 0.05 for all). BMI was identified as an independent risk factor for female-specific risk enhancers. Conclusion: CKM syndrome is prevalent among healthcare workers in Chinese tertiary hospitals, with males generally presenting at more advanced stages than females. BMI is a key predictor of CKM syndrome and female-specific risk enhancers.
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Zhang et al. (2024) conducted a cross-sectional in Cardiovascular-Kidney-Metabolic (CKM) Syndrome (n=1,110). Sedentary time > 8 hours vs. Sedentary time < 2 hours was evaluated on Cardiovascular-Kidney-Metabolic (CKM) Syndrome (OR 1.376, 95% CI 1.027-1.844, p=<0.05). More than 8 hours of sedentary time was significantly associated with an increased risk of Cardiovascular-Kidney-Metabolic Syndrome compared to less than 2 hours (OR 1.376) among healthcare workers.
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