Key result
Smoking is linked to ~2.3-fold higher odds of lower extremity arteriosclerosis obliterans.
Why the study?
Specific modifiable lifestyle risk factors associated with lower extremity arteriosclerosis obliterans in high-risk populations were not clearly identified to guide targeted primary prevention.
Do unhealthy lifestyle habits increase the incidence of lower extremity arteriosclerosis obliterans in a high-risk screening population?
Case-Control (n=300)
No
Do unhealthy lifestyle habits increase the incidence of lower extremity arteriosclerosis obliterans in a high-risk screening population?
In a high-risk screening population, modifiable lifestyle factors including smoking, prolonged sitting, poor diet, and staying up late were significant independent predictors of lower extremity arteriosclerosis obliterans development.
Answers are grounded in this paper and cite their sources.
Smoking and sedentary habits were associated with higher LEASO risk; leaves open whether lifestyle modification prevents disease in high-risk groups.
Objective: To identify specific modifiable lifestyle risk factors associated with lower extremity arteriosclerosis obliterans (LEASO) in a high-risk screening population to guide targeted primary prevention. Methods: This retrospective case-control study enrolled 300 individuals at high risk for LEASO from a tertiary hospital in Shanxi Province, China. Baseline lifestyle habits were assessed using the Lifestyle and Lower Extremity Vascular Health Questionnaire, and participants were followed for 2 years. Multivariate logistic regression was used to analyze the relationship between lifestyle habits and LEASO incidence. Results: Multivariate logistic regression identified smoking (OR = 2.289, 95% CI: 1.254– 4.178), high-salt diet (OR = 2.040, 95% CI: 1.334– 3.120), high-fat diet (OR = 1.988, 95% CI: 1.232– 3.239), high-cholesterol diet (OR = 1.571, 95% CI: 1.131– 2.183), staying up late (OR = 1.826, 95% CI: 1.119– 2.980), and prolonged sitting (OR = 2.259, 95% CI: 1.034– 4.937) as significant independent risk factors (all P < 0.05). Conclusion: In high-risk populations, specific lifestyle factors—particularly smoking, prolonged sitting, and poor dietary habits—are strongly associated with LEASO. These findings highlight the critical need for behavior-targeted community interventions to mitigate peripheral vascular disease progression.
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Bai et al. (2026) conducted a case-control in Lower extremity arteriosclerosis obliterans (LEASO) (n=300). Smoking vs. Non-smoking was evaluated on Incidence of LEASO (OR 2.289, 95% CI 1.254-4.178, p=0.007). Smoking increased the risk of developing lower extremity arteriosclerosis obliterans in a high-risk screening population, alongside prolonged sitting and poor dietary habits.
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