Key result
Fragmented QRS affects ~41% of Nigerian HF patients and is linked to reduced LVEF.
Why the study?
Fragmented QRS, QT prolongation, and wide QRS have been associated with increased risk for cardiac arrhythmias, but their prevalence and clinical correlates in Nigerians with heart failure were not described.
Cross-Sectional (n=129)
No
Answers are grounded in this paper and cite their sources.
Fragmented QRS and other depolarization abnormalities are highly prevalent in Nigerians with heart failure and correlate with markers of worse cardiac function and prior myocardial infarction.
bACKgRoUND: Fragmented QRS (fQRS), QT prolongation and wide QRS have been associated with increased risk for cardiac arrhythmias.objECTIVES: To describe the prevalence and correlates among Nigerians with heart failure.METhoDS: A total of 129 subjects were consecutively recruited for the present study.QT interval, QRS duration and fQRS were determined.SPSS version 16 was used for analysis.RESUlTS: The mean (± SD) age was 62.1±13.7 years (43.4% female).Mean QT, QTc and QRS durations were 390.4±56.2ms, 451.3±62.7 ms and 99.5±23.9ms, respectively.fQRS, QTc prolongation and wide QRS occurred in 41.1%, 44.2% and 41.9%, respectively, of study participants.fQRS appeared to be more likely associated with prolonged QTc, increased heart rate, presence of old myocardial infarction and wide QRS duration among study participants.CoNClUSIoN: fQRS, QTc prolongation and wide QRS are frequent among Nigerians with heart failure.Appropriate screening for heart failure is suggested for early intervention.
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Adeseye A. Akintunde (2015) conducted a cross-sectional in Heart failure (n=129). Fragmented QRS (fQRS) vs. Absence of fQRS was evaluated on Prevalence of fragmented QRS (fQRS). Fragmented QRS was present in 41.1% of Nigerian patients with heart failure and was significantly associated with prolonged QTc, wide QRS, old myocardial infarction, and reduced ejection fraction.
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