Key result
Epigastric flap creation with distal ligation boosts 1-day rat vein patency ~22% over basic anastomoses.
Why the study?
The study aimed to examine short-term patency of rat femoral vein anastomoses and the influence of epigastric flap creation and distal femoral vessel ligation on venous patency.
Does epigastric flap creation and distal femoral vessel ligation improve short-term patency of rat femoral vein anastomoses?
Population
Rat femoral vein model
Comparison
Epigastric flap creation and/or distal femoral vessel ligation vs basic femoral vein anastomoses
Design
Preclinical experimental study
Follow-up
1 and 7 days
Authors
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Supports tension reduction for venous patency in rat microsurgery models; leaves open clinical translation.
Does epigastric flap creation and distal femoral vessel ligation improve short-term patency of rat femoral vein anastomoses?
Absolute Event Rate: 100% vs 82%
p-value: p=<0.01
Reduction of longitudinal tension and creation of island/free flaps beneficially influence the prevention of venous occlusion in rat femoral vein anastomoses.
Cooley et al. (1992) studied Rat femoral vein anastomoses. Epigastric flap creation and ligated/transected distal femoral vessel circulation vs. Basic femoral vein anastomoses was evaluated on Patency at one day (p=<0.01). Epigastric flap creation with ligated/transected distal femoral vessel circulation increased 1-day patency of rat femoral vein anastomoses compared to basic anastomoses (100% vs 82%, P<0.01).
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