Key result
Rat aortic baroreceptor neurons exhibit T-type calcium currents in ~63% of cells alongside high-threshold currents.
Why the study?
Calcium currents in identified rat aortic baroreceptors were not previously characterized in detail.
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Hypothesis-generating for baroreceptor calcium signaling; leaves open in vivo and human translation.
Mendelowitz et al. (1992) studied this question. Voltage-clamp characterization of calcium currents was evaluated on Characterization of calcium currents. Rat aortic baroreceptor neurons possess both low-threshold (T-type) calcium currents (in 63% of cells) and high-threshold calcium currents with complex voltage-dependent inactivation kinetics.
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