Hereditary Fibromuscular Dysplasia with Renovascular Hypertension

Letters1 May 1977Hereditary Fibromuscular Dysplasia with Renovascular HypertensionP. MAJOR, M.D., J. GENEST, M.D., F.A.C.P., F.R.C.P., P. CARTIER, M.D., O. KUCHEL, M.D., F.R.C.P.P. MAJOR, M.D., J. GENEST, M.D., F.A.C.P., F.R.C.P., P. CARTIER, M.D., O. KUCHEL, M.D., F.R.C.P.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-86-5-583_1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptDysplasias of the renal arteries have been increasingly recognized, but their cause remains controversial. The findings of renal artery abnormalities in three hypertensive sisters have been reported as evidence of an hereditary developmental weakness of the renal arteries (1). We report the findings of fibromuscular hyperplasia of the right renal artery in two women who were daughters of identical twin mothers, in support of the concept of a genetic abnormality.Our patient, unaware of any consanguinity in her family, was a 41-year-old white woman known to have had labile hypertension for the previous 3 years. She consulted her physician because...References1. HALPERNSANDFORDVIAMONTE MHM: Renal-artery abnormalities in three hypertensive sisters. Probable familial fibromuscular hyperplasia. JAMA 194:512-513, 1965 CrossrefMedlineGoogle Scholar2. HARRISONHUNTBERNATZ EJP: Morphology of fibromuscular dysplasia of the renal artery in renovascular hypertension. Am J Med 43:97-112, 1967 CrossrefMedlineGoogle Scholar3. WYLIEPERLOFFWELLINGTON EDJ: Fibromuscular hyperplasia of the renal arteries. Ann Surg 156:592-607, 1962 CrossrefMedlineGoogle Scholar4. PLAGNOLGILLETCAMBUZAT PJJ: J Radiol Electrol Med Nucl 56:173-174, 1975 (French, with English summary) MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Clinical Research Institute of Montreal 110 Pine Avenue West Montreal, PQ H2W 1R7 Canada PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byFMD and SCAD: Sex-Biased Arterial Diseases With Clinical and Genetic PleiotropyCurrent progress in clinical, molecular, and genetic aspects of adult fibromuscular dysplasiaFirst International Consensus on the diagnosis and management of fibromuscular dysplasiaFirst international consensus on the diagnosis and management of fibromuscular dysplasiaSpontaneous Coronary Artery Dissection: Current State of the Science: A Scientific Statement From the American Heart AssociationRevisiting Fibromuscular DysplasiaEpidemiology of fibromuscular dysplasia: A review of the literatureRecent Developments in the Understanding and Management of Fibromuscular DysplasiaFibromuscular Dysplasia: State of the Science and Critical Unanswered QuestionsLow yield of genetic testing for known vascular connective tissue disorders in patients with fibromuscular dysplasiaRenovascular Hypertension and Ischemic NephropathyInheritance of arterial lesions in renal fibromuscular dysplasiaPathologie des artè;res rénalesIsolated Visceral Small Artery Fibromuscular Hyperplasia-Induced Ischemic Colitis Mimicking Inflammatory Bowel DiseaseMultivisceral Fibromuscular Dysplasia in Childhood: Case Report and Review of the LiteratureFamilial syndrome of progressive arterial occlusive disease consistent with fibromuscular dysplasia, hypertension, congenital cardiac defects, bone fragility, brachysyndactyly, and learning disabilitiesPossible familial origin of multifocal renal artery fibromuscular dysplasiaSouthwestern Internal Medicine Conference: Current Concepts in Renovascular HypertensionEtiologic factors in renovascular fibromuscular dysplasia. A case-control study.Clinical Significance of Cerebral Aneurysm in Renovascular Hypertension due to Fibromuscular Dysplasia: Two Cases in SiblingsFibromuscular Arterial DysplasiasNeurofibromatosis and renal artery stenosis: A case of familial incidenceFamilial occurrence of spontaneous dissection of the internal carotid artery.Fibromuscular Dysplasia of the Internal Carotid ArteryFibromuscular dysplasia and the brain. II. Current concept of the disease. 1 May 1977Volume 86, Issue 5Page: 583-583KeywordsDysplasiaGeneticsHypertensionMonozygotic twinsRenal arteries Issue Published: 1 May 1977 PDF downloadLoading ...