Key result
Telemetered exercise ECG induces ST depression in ~93% of children with 50-100 mmHg aortic gradients.
Why the study?
Does telemetered exercise electrocardiogram accurately identify severe congenital aortic stenosis in children compared to resting ECG?
Population
56 children, comprising 31 with congenital aortic valve stenosis and 25 normal children of comparable age.
Comparison
Telemetered exercise electrocardiogram vs Resting electrocardiogram, vectorcardiogram, and…
Design
Cross-sectional
Authors
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Exercise-induced ST depression was associated with severe aortic stenosis in children; hypothesis-generating and requires prospective validation before clinical use.
Cross-Sectional (n=56)
Does telemetered exercise electrocardiogram accurately identify severe congenital aortic stenosis in children compared to resting ECG?
Absolute Event Rate: 93.3% vs 6.25%
Exercise electrocardiography is highly specific for identifying children with severe congenital aortic stenosis (gradients ≥50 mm Hg), outperforming resting ECG.
Katherine H. Halloran (1971) conducted a cross-sectional in Congenital aortic stenosis (n=56). Telemetered exercise electrocardiogram vs. Normal children and patients with gradients <50 mm Hg was evaluated on S-T segment depression in lead V5 of 2 mm or greater. Telemetered exercise electrocardiography induced S-T segment depression in 93.3% of children with aortic gradients of 50-100 mm Hg, versus 6.25% with gradients <50 mm Hg and 0% of normal controls.
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