Key result
Rotavirus-associated benign convulsion linked to a transient corpus callosum lesion resolving in 6 days.
Why the study?
Few case reports exist on reversible splenial corpus callosum lesions associated with rotavirus infection in benign convulsion with mild gastroenteritis.
Case Report (n=1)
No
Rotavirus-associated benign convulsion with mild gastroenteritis can present with a reversible transient splenial lesion of the corpus callosum on MRI.
May indicate reversible splenial lesions in rotavirus-associated benign convulsions; leaves open whether MRI alters management in this population.
Transient magnetic resonance (MR) signal changes in the splenium of the corpus callosum (SCC) arise from many different conditions, including encephalopathy or encephalitis caused by infection, seizures, metabolic derangements, and asphyxia. Few case reports exist on reversible SCC lesions associated with rotavirus infection. A benign convulsion with mild gastroenteritis (CwG) is frequently associated with rotaviral infections. This entity is characterized by normal laboratory findings, electroencephalogram, neuroimaging, and good prognosis. We report a case of a 2.5-year-old Korean girl with rotavirus-associated CwG demonstrating a reversible SCC lesion on diffusion-weighted MR images. She developed 2 episodes of brief generalized tonic-clonic seizure with mild acute gastroenteritis without any other neurologic abnormality. Stool test for rotavirus antigen was positive. Brain MRI done on the day of admission showed a linear high signal intensity and decreased apparent diffusion coefficient values on the SCC. The lesion completely disappeared on follow-up MRI 6 days later. The patient fully recovered without any sequelae.
No takes yet. Share an insight, caveat, or question.
Jang et al. (2010) conducted a case report in Benign convulsion with mild gastroenteritis (CwG) associated with rotavirus infection (n=1). Rotavirus infection was evaluated on Resolution of splenial lesion of the corpus callosum. A 2.5-year-old girl with rotavirus-associated benign convulsion with mild gastroenteritis developed a transient splenial lesion of the corpus callosum that completely resolved within 6 days.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: