Key result
Diffusion-weighted MRI demonstrated a reversible lesion with restricted proton diffusion in the splenium of the corpus callosum more conspicuously than other MRI techniques.
Why the study?
Does diffusion-weighted MRI improve detection of early changes in rotavirus encephalopathy compared to other MRI techniques?
Case Report (n=1)
Does diffusion-weighted MRI improve detection of early changes in rotavirus encephalopathy compared to other MRI techniques?
Diffusion-weighted MRI is potentially useful for detecting early, reversible changes in rotavirus encephalopathy.
May aid early detection of reversible splenial lesions in rotavirus encephalopathy; leaves open need for prospective validation before routine use.
The authors report serial brain MR findings from a 2-year-old girl with rotavirus encephalopathy. The lesion in the splenium of the corpus callosum showed restricted proton diffusion, suggesting local cytotoxic edema. Diffusion-weighted images demonstrated the lesion more conspicuously than other techniques, such as fluid-attenuated inversion-recovery and T1- and T2-weighted images. The findings were reversible on follow-up MRI obtained 4 days later. Diffusion-weighted MRI is a potentially useful method for detecting early changes of rotavirus encephalopathy, although the mechanism of the restricted diffusion is not clearly identified.
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Kobata et al. (2002) conducted a case report in Rotavirus encephalopathy (n=1). Diffusion-weighted MRI vs. Fluid-attenuated inversion-recovery and T1- and T2-weighted images was evaluated on Lesion visibility and restricted proton diffusion in the splenium of the corpus callosum. Diffusion-weighted MRI demonstrated a reversible lesion with restricted proton diffusion in the splenium of the corpus callosum more conspicuously than other MRI techniques.
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