Key result
OSA in T2DM is linked to ~2.7% higher HbA1c and reduced peak expiratory flow.
Why the study?
Obstructive sleep apnoea is not routinely screened in type 2 diabetes mellitus, and its impact on blood glucose control and pulmonary functions is poorly studied.
Does the presence of obstructive sleep apnoea impair blood glucose control and pulmonary functions in patients with type 2 diabetes mellitus?
Cross-Sectional (n=104)
No
Does the presence of obstructive sleep apnoea impair blood glucose control and pulmonary functions in patients with type 2 diabetes mellitus?
Absolute Event Rate: 11.48% vs 8.75%
p-value: p=0.029
In patients with type 2 diabetes, comorbid obstructive sleep apnea is associated with impaired blood glucose control and decreased pulmonary function.
May support OSA evaluation in poorly controlled T2DM; hypothesis-generating, prospective trials needed before practice change.
Background: Obstructive sleep apnoea (OSA) has an increased prevalence in type 2 Diabetes mellitus (T2DM) .OSA as a co morbid condition in T2DM is associated with insulin resistance.Type 2 Diabetes mellitus is associated with many systemic complications and it includes involvement of lungs also .OSA is asymptomatic disorder which is not routinely screened in T2DM.OSA and lung involvement in diabetes are associated with poor oxygen saturation of blood.The impact of OSA in blood glucose control and pulmonary functions are poorly studied Methods: This prospective cross sectional study was conducted on T2DM patients in a tertiary care hospital.About 104 T2DM patients recruited from department of general medicine.Stop Bang questionnaire was used evaluate the presence of OSA.Pulmonary function test assessed with computerized spirometer.The Patient's FBS, PPBS HbA1c and anthropometry were measured.Based on the presences of OSA, T2D Patients grouped in to two categories.Group 1 -T2 DM with OSA and group 2 T2DM without OSA.Influence of OSA on blood glucose studied by comparing the variables between two groups Results: A total of 104 T2DM studied .A total of 52 patients in the OSA group and 52 in Non-OSA group were encountered.OSA scores showed a positive correlation with weight and duration of diabetes and a negative correlation with FEV1 and PEFR Conclusions: Obstructive sleep apnoea thus causes an impairment in the blood glucose control.OSA may cause a decreases in the pulmonary functions
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Latha Sannasi (2019) conducted a cross-sectional in Type 2 Diabetes Mellitus (n=104). Obstructive Sleep Apnoea (OSA) vs. Type 2 Diabetes Mellitus without OSA was evaluated on HbA1c (%) (p=0.029). In patients with Type 2 diabetes mellitus, the presence of obstructive sleep apnoea was associated with significantly higher HbA1c levels (11.48% vs 8.75%, p=0.029) and reduced peak expiratory flow.
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