Background:This study aimed to determine the impact of radial artery (RA) hyperperfusion on the first-attempt success rate of arterial catheterization and the accuracy of arterial blood gas analysis in patients with acute heart failure (AHF).Methods:From March 2024 to January 2026, 356 patients with AHF admitted to the Emergency Department of our hospital were enrolled and randomly assigned to either a non-hyperperfusion group or a hyperperfusion group (178 patients per group). Randomization was performed using a random number table. The non-hyperperfusion group received conventional blind radial artery catheterization, whereas the hyperperfusion group underwent catheterization under a hyperperfusion intervention. In the hyperperfusion group, blood gas analysis samples obtained via catheter were collected once in each of the conventional and hyperperfusion conditions. The first-time success rate of RA catheterization, catheterization time, pain score, and heart rate fluctuation were compared between the two groups. In addition, we explored the impact of hyperperfusion blood collection on the precision of blood gas analysis outcomes.Results:The first-attempt success rate of RA catheter insertion, catheterization time, pain score, and heart rate changes in the hyperperfusion group were better than those observed in the non-hyperperfusion group, with the differences being statistically significant (p < 0.05). There was no significant difference in lactic acid, pH, PaCO2, PaO2, Na+, K+, and SaO2 in the blood gas analysis under the hyperperfusion state compared with that in the conventional state (p > 0.05).Conclusions:The hyperperfusion method improved the first-attempt success rate of RA catheterization in patients with AHF, shortened catheterization time, reduced patient pain, and had no significant effect on the accuracy of RA blood gas analysis.Clinical Trial Registration:ChiCTR2500113153, https://www.chictr.org.cn/showproj.html?proj=297512.
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