Key result
CFA IMT ≥8.5 mm strongly predicts subclinical PAD in elderly T2D patients.
Why the study?
Thickened carotid intima media thickness is an accepted surrogate marker for vascular disease, but the ability of common femoral artery intima media thickness to predict subclinical peripheral arterial disease in elderly type 2 diabetes patients needed evaluation.
Does common femoral artery intima media thickness predict subclinical peripheral arterial disease in elderly patients with type 2 diabetes mellitus?
Cross-Sectional (n=60)
Does common femoral artery intima media thickness predict subclinical peripheral arterial disease in elderly patients with type 2 diabetes mellitus?
Effect estimate: AUC 0.962 (95% CI 0.917-1.007)
p-value: p=0.000
Thickened common femoral artery intima media thickness (≥ 8.5 mm) is a strong predictor of asymptomatic peripheral arterial disease in elderly patients with type 2 diabetes.
May aid subclinical PAD screening in elderly type 2 diabetes; hypothesis-generating and requires prospective validation before practice change.
Background: Thickening of ar terial wal l is an early indicator of atherosclerosis which is mostly a poly vasculardisease. Thickened carotid intima media thickness is now wel l accepted as a sur rogate marker for cardiovascular ,cerebrovascular , and peripheral vascular a ffection. Some data exists regarding the relationship between intima mediathickness of the common femoral artery as a predictor of di fferent vascular beds atherosclerosis..Aim: To evaluate the abi l i ty of common femoral artery intima media thickness to pr edict subcl inical peripheralar terial disease in elderly patients wi th type 2 diabetes mel l i tus.Methods: 60 elderly subjects wi th type 2 diabetes were examined for the presence of asymptomatic PAD. Al l wereassessed by measuring Common Femoral Artery Intima Media Thickness CFA IMT, ankle brachial index (ABI) .Results: The patients with reduced ABI (N=9) had greater CFA-IMT than those without (N=51). The correlationbetween CFA-IMT and ABI was highly significant. CFA IMT≥ 8.5 mm had an area under the curve of 0.962 (95% CI;0.917- 1.007, p = 0.000*) for predicting subclinical PAD in patients with type 2 diabetes.Conclusions: This data suggests that thickened CFA IMT is a signi ficant predictor of asymptomatic PAD in patien tswi th type 2 diabetes
No takes yet. Share an insight, caveat, or question.
Ms et al. (2017) conducted a cross-sectional in Type 2 diabetes mellitus (n=60). Common Femoral Artery Intima Media Thickness (CFA IMT) was evaluated on Subclinical peripheral arterial disease (reduced ankle brachial index) (AUC 0.962, 95% CI 0.917-1.007, p=0.000). Common femoral artery intima media thickness ≥8.5 mm strongly predicted subclinical peripheral arterial disease in elderly patients with type 2 diabetes (AUC 0.962; 95% CI 0.917-1.007; p=0.000).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: