Key result
PBMV in severe MS with moderate MR yields similar 30-day major events versus less MR.
Why the study?
Does percutaneous balloon mitral valvotomy safely improve outcomes in patients with severe mitral stenosis and moderate mitral regurgitation?
Population
225 patients with severe mitral stenosis, divided into Group I with moderate mitral regurgitation and Group…
Comparison
Percutaneous balloon mitral valvotomy (PBMV) vs Patients with severe MS and less than moderate…
Design
Cohort
Follow-up
6 months
Authors
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May support PBMV consideration in moderate MR; leaves open randomized trials before practice change.
Cohort (n=225)
Does percutaneous balloon mitral valvotomy safely improve outcomes in patients with severe mitral stenosis and moderate mitral regurgitation?
Absolute Event Rate: 11.7% vs 3.85%
p-value: p=0.36
PBMV may be a safe and effective option for patients with severe mitral stenosis and moderate mitral regurgitation, providing sustained symptomatic benefit despite a higher risk of developing severe MR.
Vinayakumar et al. (2016) conducted a cohort in Severe mitral stenosis with moderate mitral regurgitation (n=225). Moderate mitral regurgitation vs. Less than moderate or no mitral regurgitation was evaluated on Composite of cardiovascular death and development of severe MR with or without requirement for mitral valve replacement at 30 days of procedure (p=0.36). PBMV in severe mitral stenosis with moderate MR yielded similar 30-day rates of cardiovascular death or severe MR compared to less MR (11.7% vs 3.85%, p=0.36).
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