Key result
PBMV linked to enlarged mitral orifice, reduced left atrial diameter, and decreased regurgitation area.
Why the study?
The effectiveness of percutaneous balloon mitral valvuloplasty for rheumatic mitral stenosis in patients with mild to severe mitral regurgitation was not established.
Does percutaneous balloon mitral valvuloplasty (PBMV) improve echocardiographic parameters in Chinese patients with rheumatic mitral stenosis and mild to severe mitral regurgitation?
Observational (n=56)
Does percutaneous balloon mitral valvuloplasty (PBMV) improve echocardiographic parameters in Chinese patients with rheumatic mitral stenosis and mild to severe mitral regurgitation?
Percutaneous balloon mitral valvuloplasty effectively enlarges the mitral orifice and reduces left atrial diameter in rheumatic mitral stenosis, while paradoxically decreasing the regurgitation area in patients with baseline moderate to severe regurgitation.
May support PBMV in rheumatic MS with MR; hypothesis-generating and requires randomized confirmation before practice change.
This study is designed to test whether percutaneous balloon mitral valvuloplasty (PBMV) is effective for rheumatic mitral stenosis in Chinese patients with moderate to severe mitral regurgitation. Fifty-six patients with rheumatic mitral valve stenosis were divided into the mild, moderate, and severe regurgitation groups. Cardiac ultrasonography was measured before and 1 to 2 days after PBMV. Following PBMV, the mitral orifice was enlarged, and the left atrial diameter was reduced in the 3 patient groups. The enlargement of the mitral orifice in the mild regurgitation group was greater than that observed in the moderate and severe regurgitation groups. The size of the regurgitation area increased in the mild regurgitation group and decreased in the moderate and severe regurgitation groups, with the decrease in the severe regurgitation group being greater than that in the moderate regurgitation group. Therefore, PBMV is effective for treating rheumatic mitral stenosis in Chinese patients with mild to severe mitral regurgitation.
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Lu et al. (2016) conducted an observational in Rheumatic mitral stenosis with mild to severe mitral regurgitation (n=56). Percutaneous balloon mitral valvuloplasty vs. Baseline (before procedure) was evaluated on Mitral orifice size, left atrial diameter, and regurgitation area. Percutaneous balloon mitral valvuloplasty enlarged the mitral orifice and reduced left atrial diameter, while decreasing the regurgitation area in patients with moderate to severe regurgitation.
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