Key result
Catheter ablation reduces mortality and HF hospitalization versus medical therapy in AF and HF patients.
Why the study?
The comparative effects of catheter ablation versus medical therapy on mortality and hospitalization in patients with atrial fibrillation and heart failure were unclear.
Does catheter ablation reduce mortality and hospitalization for worsening HF compared to medical therapy in patients with AF and HF?
Does catheter ablation reduce mortality and hospitalization for worsening HF compared to medical therapy in patients with AF and HF?
In patients with AF and HF, catheter ablation reduces mortality and hospitalization for worsening HF compared to medical therapy.
Supports ablation in AF-HF; leaves open confirmation by prospective RCTs before practice change.
ACP Journal Club15 May 2018In AF and HF, catheter ablation vs medical therapy reduced mortality and hospitalization for worsening HFBrian Greet, MD, Paul Schurmann, MD, Anita Deswal, MD, MPHBrian Greet, MDBaylor College of Medicine, Houston, Texas, USA (B.G., P.S.)Search for more papers by this author, Paul Schurmann, MDBaylor College of Medicine, Houston, Texas, USA (B.G., P.S.)Michael E. DeBakey VA Medical Center and Baylor College of Medicine, Houston, Texas, USA (P.S., A.D.)Search for more papers by this author, Anita Deswal, MD, MPHMichael E. DeBakey VA Medical Center and Baylor College of Medicine, Houston, Texas, USA (P.S., A.D.)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/ACPJC-2018-168-10-055 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Source CitationMarrouche NF, Brachmann J, Andresen D, et al; CASTLE-AF Investigators. Catheter ablation for atrial fibrillation with heart failure. N Engl J Med. 2018;378:417-27. https://pubmed.ncbi.nlm.nih.gov/29385358Clinical Impact RatingsCardiology: Reference1 January CT, Wann LS, Alpert JS, et al.; American College of Cardiology/American Heart Association Task Force on Practice Guidelines. 2014 AHA/ACC/HRS guideline for the management of patients with atrial fibrillation: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the Heart Rhythm Society. J Am Coll Cardiol. 2014;64:e1-76. [PMID: 24685669]. Google Scholar Author, Article, and Disclosure InformationAffiliations: Baylor College of Medicine, Houston, Texas, USA (B.G., P.S.)Michael E. DeBakey VA Medical Center and Baylor College of Medicine, Houston, Texas, USA (P.S., A.D.)This article was published at Annals.org on 1 May 2018. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 15 May 2018Volume 168, Issue 10Page: JC55KeywordsAtrial fibrillationCardiac ablationCathetersHeartHeart failureHospitalizationsLeft ventricular ejection fractionMortalityPatientsTreatment guidelines ePublished: 15 May 2018 Issue Published: 15 May 2018 Copyright & PermissionsCopyright © 2018 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
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Greet et al. (2018) conducted a review in Atrial fibrillation and heart failure. Catheter ablation vs. Medical therapy was evaluated on Mortality and hospitalization for worsening heart failure. Catheter ablation reduced mortality and hospitalization for worsening heart failure compared to medical therapy in patients with atrial fibrillation and heart failure.
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