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Clinical review demonstrates the clinical impact of thrombophilia in ischemic stroke patients, highlighting the need for tailored secondary prevention.
Ischemic stroke is mainly provoked by atherosclerotic changes in cerebral arteries or thromboembolic episodes related to cardiac arrhythmias.Less frequently, especially in the younger patients stroke may be related to hypercoagulable states.Detection of thrombophilia requires specialized diagnostic procedures and in some situations change patients' management.Presence of thrombophilia may influence decision to close patent foramen ovale in a patient after ischemic stroke.On the other hand, antiphospholipid syndrome diagnosis influences the choice of antithrombotic treatment in the secondary prevention of stroke.
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Jacek Musiał (2023) studied this question.
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