Key result
High preoperative systemic immune-inflammation index linked to ~258% greater 30-day complication risk after tricuspid surgery.
Why the study?
The systemic immune-inflammation index has emerged as an inflammatory marker, but its prognostic implications in patients undergoing isolated tricuspid valve surgery were unknown.
Does a high preoperative systemic immune-inflammation index predict short-term outcomes in patients undergoing isolated tricuspid valve surgery?
Population
213 patients undergoing isolated tricuspid valve surgery between January 2000 and December 2018
Comparison
High preoperative SII (≥455.6 × 109/L) vs low preoperative SII (<455.6 × 109/L)
Design
Retrospective observational cohort study
Follow-up
30 days
Authors
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May support preoperative risk stratification in isolated tricuspid valve surgery; hypothesis-generating pending prospective validation.
Cohort (n=213)
Does a high preoperative systemic immune-inflammation index predict short-term outcomes in patients undergoing isolated tricuspid valve surgery?
Hazard Ratio: 3.58 (95% CI 1.62–7.95)
p-value: p=0.001
Preoperative systemic immune-inflammation index is a readily available parameter that independently predicts major 30-day postoperative complications in patients undergoing isolated tricuspid valve surgery.
Yoon et al. (2021) conducted a cohort in Isolated tricuspid valve surgery (n=213). High preoperative systemic immune-inflammation index (SII ≥455.6 × 10^9/L) vs. Low systemic immune-inflammation index (SII <455.6 × 10^9/L) was evaluated on All-cause mortality and major postoperative complications within a 30-day period (HR 3.58, 95% CI 1.62-7.95, p=0.001). High preoperative systemic immune-inflammation index was associated with major 30-day postoperative complications after isolated tricuspid valve surgery (HR 3.58; 95% CI 1.62-7.95; p=0.001).
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