Why the study?
The term hypertensive urgency was abolished in new Russian Society of Cardiology guidelines and management changed, requiring clarity on managing sudden symptomatic blood pressure increases without overt target organ damage.
Does captopril effectively manage sudden individually significant blood pressure increases without target organ damage in symptomatic patients?
Does captopril effectively manage sudden individually significant blood pressure increases without target organ damage in symptomatic patients?
Expert consensus supports the use of captopril for the self-management of sudden, symptomatic blood pressure increases without target organ damage.
Supports outpatient self-management of symptomatic BP surges with captopril; reinforces Level 1 guideline consensus on rapid-onset agents.
Expert Council opinion describes emergency care in a sudden individually significant blood pressure (BP) increase without clinically overt target organ damage. In the new guidelines of the Russian Society of Cardiology, the term “hypertensive urgency” was abolished, and the management of a sudden BP increase was changed. At the same time, a sudden individually significant BP increase may be accompanied by symptoms that reduce patients’ quality of life and ability to work. According to experts, individually significant BP increase accompanied by symptoms requires outpatient treatment using oral rapid-onset drugs with an optimal duration of action, in particular captopril. It has a much evidence-based data on the BP increase use and sublingual administration, and also has a favorable safety profile, which allows prescribing to patients with comorbid diseases. The rationale for the use of angiotensin-converting enzyme inhibitor Capoten (captopril) as a drug for self-management of a sudden individually significant BP increase accompanied by symptoms in hypertension patients is describes.
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Терещенко et al. (2020) conducted a review in Sudden individually significant blood pressure increase without clinically overt target organ damage. Captopril was evaluated. Expert consensus supports the use of oral rapid-onset drugs, particularly captopril, for outpatient self-management of sudden individually significant blood pressure increases accompanied by symptoms.
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