Key result
B mode ultrasound detects carotid stenosis with ~81% sensitivity while OPG and Doppler yield high specificity.
Why the study?
The accuracy of various non-invasive methods for evaluating extracranial carotid artery disease compared to carotid angiography was unclear.
What is the diagnostic accuracy of non-invasive methods (CPA, OPG, SOD, B mode ultrasound) compared to carotid angiography in assessing extracranial carotid artery disease?
Observational (n=67)
What is the diagnostic accuracy of non-invasive methods (CPA, OPG, SOD, B mode ultrasound) compared to carotid angiography in assessing extracranial carotid artery disease?
Combining B mode ultrasound with OPG or Doppler provides improved overall accuracy in the non-invasive assessment of extracranial carotid stenosis.
May inform non-invasive test selection for carotid stenosis; leaves open prospective validation against angiography in larger cohorts.
The accuracy of four-invasive methods used in the evaluation of the extracranial carotid arterial system are presented. Three of the methods were the flow dependent whilst the fourth was an ultrasonic imaging system. A consecutive series of 67 patients, (134 carotid arteries), having carotid angiography were investigated by means of carotid phonoangiography (CPA), oculoplethysmography (OPG), supra orbital Doppler (SOD) and B mode ultrasound scanning. The sensitivity of the B mode ultrasound was 81% with the OPG, CPA and Doppler method yielding sensitivities of 51%, 56% and 63% respectively. The specificity of both the OPG 95% and the Doppler 90% wqs high. The combined use of both B Mode ultrasound and OPG or Doppler will provide an improved overall accuracy in the assessment of extra cranial carotid stenosis.
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Appleberg et al. (1982) conducted an observational in Extracranial carotid artery disease (n=67). Non-invasive diagnostic methods (B mode ultrasound, OPG, CPA, SOD) vs. Carotid angiography was evaluated on Sensitivity for detecting extracranial carotid stenosis. B mode ultrasound demonstrated a sensitivity of 81% for detecting extracranial carotid stenosis, while OPG and Doppler methods yielded high specificities of 95% and 90%, respectively.
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