Together with silvaticol (11), nidulol (12), ergosterol, paxilline (10), and mannitol, three new bicoumarins designated as desertorin A (1)(C22H18O8), B (2)(C23H20O8), and C (3)(C26H22O8) have been isolated from Emericella desertorum, strain CBS 653.73. The structures of desertorins A (1), B (2), and C (3) were determined on the basis of the spectroscopic and chemical investigations of these compounds and their derivatives i.e., as 7,7′-dihydroxy-4,4′-dimethoxy-5,5′-dimethyl-6,8′-bicoumarin, 5,5′-dimethyl-6,8′-bicoumarin, 5,5′-dimethyl-7-hydroxy-4,4′,7′-trimethoxy-6,8′-bicoumarin and 5,5′-dimethyl-4,4′,7,7′-tetramethoxy-6,8′-bicoumarin, respectively. It is interesting to note that silvaticol (11) and nidulol (12), both of the known metabolites of Aspergillus silvaticus, were isolated from the same extracts.
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Nozawa et al. (1987) studied this question.