Key result
Treated hypertensive men with the lowest urinary sodium excretion had the highest incidence of myocardial infarction, though methodological concerns raise doubts about these findings.
Why the study?
Does a low-sodium diet reduce cardiovascular disease in treated hypertensive men and women?
Does a low-sodium diet reduce cardiovascular disease in treated hypertensive men and women?
Answers are grounded in this paper and cite their sources.
This editorial highlights a study suggesting that severe dietary sodium restriction may be associated with increased myocardial infarction in treated hypertensive men, challenging conventional wisdom.
Because a low-sodium diet is often recommended as part of the treatment to control hypertension, a recent study examined the relationship between sodium intake, 24-hour urinary sodium excretion, and subsequent cardiovascular disease in treated hypertensive men and women. Contrary to expectations, the men with the lowest urinary sodium excretion had the highest incidence of myocardial infarction. Concerns about the group studied and some of the measurements used raise doubt about the results of this study, especially in light of the weight of data from population studies supporting a link between low blood pressure and low sodium intake. However, should future studies corroborate this one, clinicians will need to re-evaluate the simple notion that severe dietary sodium restriction is always beneficial for people with hypertension.
No takes yet. Share an insight, caveat, or question.
James C. Fleet (2009) conducted an editorial in Hypertension. Low urinary sodium excretion was evaluated on Myocardial infarction. Treated hypertensive men with the lowest urinary sodium excretion had the highest incidence of myocardial infarction, though methodological concerns raise doubts about these findings.
Synapse has enriched 10 related papers. Consider them for comparative context: