Dietary Resistant Maltodextrin Attenuates Skeletal Muscle Atrophy in Association with Modulation of the Microbiota–Gut–Muscle Axis in Aged Mice

under HFD. RMD also increased fecal SCFA levels under HFD conditions and was associated with increased expression of PI3K/Akt/mTOR-related and myogenic genes in skeletal muscle. These findings indicate that RMD attenuates skeletal muscle atrophy in aged mice in association with changes in gut microbiota composition, microbial metabolites, and muscle-related gene expression.