Key result
DE-MRI hyperenhancement in ~62% of symptomatic apical HCM patients links to systolic dysfunction and arrhythmias.
Why the study?
The intramural distribution of myocardial hyperenhancement and its correlation with clinical symptoms, ventricular arrhythmias, and cardiac function have not been described for symptomatic apical HCM.
Comparison
Myocardial hyperenhancement presence vs absence
Design
Observational MRI study
Authors
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May support DE-MRI for arrhythmic risk assessment in apical HCM; leaves open prospective validation before clinical adoption.
Observational (n=13)
In symptomatic apical HCM, DE-MRI frequently reveals subendocardial hyperenhancement that correlates with regional systolic dysfunction, serious symptoms, and ventricular arrhythmias.
Amano et al. (2011) conducted an observational in Symptomatic apical hypertrophic cardiomyopathy (n=13). Myocardial hyperenhancement on delayed-enhancement MRI was evaluated on Presence of apical myocardial hyperenhancement. Myocardial hyperenhancement on delayed-enhancement MRI was found in 61.5% of patients with symptomatic apical HCM and was associated with regional systolic dysfunction and ventricular arrhythmias.
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