Key result
Moderate interval training reduces pulse pressure by ~13 mmHg versus sedentary controls.
Why the study?
Pulse pressure might be a stronger determinant of cardiovascular risk, but the effect of interval training on pulse pressure in hypertension was unclear.
Does an 8-week interval training program reduce pulse pressure in male patients with mild to moderate essential hypertension?
RCT (n=245)
Double-blind
Randomized
No
Does an 8-week interval training program reduce pulse pressure in male patients with mild to moderate essential hypertension?
Absolute Event Rate: -12.98% vs 3.67%
p-value: p=<0.001
Moderate intensity interval training effectively reduces pulse pressure and blood pressure in men with mild to moderate hypertension.
Moderate-intensity interval training reduces pulse pressure in hypertension; reinforces exercise as effective nonpharmacological adjunct and supports outcome trials.
BACKGROUND: Pulse pressure (PP), might be a stronger determinants of cardiovascular risk. OBJECTIVE: To investigate the effect of interval training program on PP in subjects with hypertension. METHODS: Two hundred and forty five male patients with mild to moderate (Systolic Blood Pressure [SBP] between 140-179 & Diastolic Blood Pressure [DBP] between 90-109 mmHg) essential hypertension were age-matched and grouped into exercise and control groups. The exercise (work: rest ratio of 1:1) groups involved in an 8-weeks interval training programs of between 45-60 minutes, at intensities of 60-79% of HR max (maximum heart rate), while the control group remained sedentary during this period. SBP, DBP, VO2max and PP were assessed. RESULTS: Findings of the study revealed significant correlation between PP and blood pressure; correlation of PP with SBP was much stronger (95% variance). Also, there was significant effect of the exercise training program on SBP, DBP and PP. Changes in VO2max also negatively correlated with changes in PP (r= -.285) at p<0.05. CONCLUSION: Moderate intensity interval training programs is effective in the non-pharmacological management of hypertension and may prevent cardiovascular event through the down regulation of PP in hypertension.
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GC Okoye (2013) conducted an RCT in Mild to moderate essential hypertension (n=245). Interval training program vs. Sedentary control was evaluated on Change in pulse pressure (PP) (p=<0.001). An 8-week moderate intensity interval training program significantly reduced pulse pressure by 12.98 mmHg compared to an increase of 3.67 mmHg in the sedentary control group.
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