Key result
Controlled hypertension is linked to ~14% higher 24-hour pulse pressure versus normotensive controls.
Why the study?
It was unclear whether antihypertensive therapy alters pulse pressure independently from other blood pressure parameters in treated hypertensive patients.
Does successful antihypertensive therapy normalize 24-hour pulse pressure in hypertensive patients?
Comparison
Successfully treated hypertensives vs healthy normotensive controls and poorly treated hypertensives
Design
Cross-sectional study
Follow-up
24 hours (ambulatory blood pressure monitoring)
Authors
Loading...
Elevated 24-h pulse pressure persists despite BP control in treated hypertensives; hypothesis-generating for whether PP-targeted therapy improves outcomes.
Cross-Sectional (n=109)
No
Does successful antihypertensive therapy normalize 24-hour pulse pressure in hypertensive patients?
Absolute Event Rate: 49% vs 43%
p-value: p=<0.05
24-hour ambulatory blood pressure monitoring reveals that pulse pressure remains elevated in treated hypertensive patients despite achieving target systolic and diastolic blood pressures.
Strbova et al. (2011) conducted a cross-sectional in Essential hypertension (n=109). Antihypertensive therapy (successful blood pressure control) vs. Normotensive controls was evaluated on 24-hour pulse pressure (PP) (p=<0.05). Successfully treated hypertensive patients had significantly increased 24-hour pulse pressure compared to normotensive controls (49 vs 43 mmHg, p<0.05) despite proper control of systolic and diastolic blood pressure.