Why the study?
Do changes in pulse pressure during antihypertensive therapy correlate with changes in surrogate markers of target-organ damage (BNP and UAR) in treated hypertensive subjects?
Population
540 treated hypertensive subjects whose home systolic blood pressure (SBP) was >=135 mm Hg
Comparison
Added treatment group for 6 months vs Control group (not further specified)
Design
Cohort
Follow-up
6 months
Authors
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Home PP changes may track surrogates during therapy; hypothesis-generating and should not yet change practice.
Do changes in pulse pressure during antihypertensive therapy correlate with changes in surrogate markers of target-organ damage (BNP and UAR) in treated hypertensive subjects?
Changes in self-monitored pulse pressure during antihypertensive treatment correlate with changes in surrogate markers of target-organ damage, highlighting the value of home monitoring.
Eguchi et al. (2007) studied this question.
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