Key result
US Kawasaki disease admissions peak during winter months and are ~61% male.
Why the study?
To investigate differences in gender, month of year, race, region, total charges, and household income among children with Kawasaki disease in the United States.
Cross-Sectional (n=5,503)
Yes
In the United States, Kawasaki disease admissions predominantly affect young males, peak in the winter months, and are most prevalent among children of Asian or Pacific Islander descent.
May heighten winter suspicion for Kawasaki disease in young males; leaves open whether patterns persist or vary over time.
Kawasaki disease (KD) is a medium-sized-vessel vasculitis that affects mostly children. The 2016 Healthcare Cost and Utilization Project Kid’s Inpatient Database (HCUP KID) was used in weighted form to investigate differences in gender, month of year, race, region, total charges, and household income in the United States. 5503 weighted cases were found. It was more common in males (3345, 60.8%) than females (2158, 39.2%) (p < 0.01). Most admitted KD patients were white (1913, 38.1%). A higher prevalence of Kawasaki disease was seen among patients of Asian or Pacific Islander background (0.2%). The southern regions of the United States reported the highest rate of admission with 2036 patients (37%). The median age on admission was 2 years (interquartile range [IQR] of 1–5, p < 0.01) and the median charge was $32,170 (IQR: $20,825–$50,502.05) (p < 0.01). Most admissions of Kawasaki disease were recorded in winter with a peak in March (623, 11.3%) (p < 0.01).
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Ramphul et al. (2019) conducted a cross-sectional in Kawasaki disease (n=5,503). Demographic and seasonal factors was evaluated on Epidemiological characteristics. In 2016, Kawasaki disease admissions in the United States were predominantly male (60.8%), had a median age of 2 years, and peaked during the winter months.
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