Key result
Carotid endarterectomy resulted in a significant decrease in blood pressure in 80.3% of patients within 2-7 days postoperatively, with 39.7% requiring no antihypertensive therapy at 1 year.
Why the study?
To establish the relationship between arterial hypertension and hemodynamically significant atherosclerotic stenosis of the carotid bifurcation, and evaluate the effect of carotid endarterectomy on blood pressure.
Does carotid endarterectomy reduce blood pressure in patients with arterial hypertension and carotid stenosis?
Observational (n=320)
Does carotid endarterectomy reduce blood pressure in patients with arterial hypertension and carotid stenosis?
Carotid endarterectomy may have a prominent and stable antihypertensive effect in patients with carotid stenosis and arterial hypertension.
BACKGROUND: The aim of this study was to establish the relationship between arterial hypertension (AH) and hemodynamically significant atherosclerotic stenosis of carotid bifurcation and study the effect of carotid endarterectomy (CEA) on the course of AH. METHODS: In our investigation we included 320 patients: 243 (75.9%) men and 77 (24.1%), the mean age - 59.6±8.2. All patients underwent CEA operation. Patients were divided into groups: I (320) - before CEA surgery and AH; II (320) - the same patients after CEA operation. All patients underwent laboratory tests, ECG, chest X-ray, ultrasound of the kidneys, thyroid gland, computer tomography (CT) of adrenal glands, of the brain, echocardiography, ultrasound or angiography of the renal arteries. Before and after the CEA, there were made Doppler ultrasound of brachiocephalic arteries, 24 hours blood pressure (BP) monitoring. Additional visits were made by 73 patients in 3, 6 and 12 months after the CEA. RESULTS: Most of the patients had significant decrease of BP in the postoperative period, which was observed in 257 (80.3%) patients on days 2-7, in 58 (18.1%) - did not change significantly, and only 5 (1.6%) had the increasing of BP. In 29 (39.7%) patients 1 year after CEA, there was no need to use antihypertensive therapy due for the normalization of BP after the surgery. CONCLUSIONS: It is necessary to highlight the cerebrovascular AH into a separate form of the secondary AH. The CEA has prominent, stable antihypertensive effect on these patients.
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Germanova et al. (2022) conducted an observational in Arterial hypertension and atherosclerotic stenosis of carotid bifurcation (n=320). Carotid endarterectomy (CEA) vs. Before CEA surgery was evaluated on Significant decrease of blood pressure on days 2-7. Carotid endarterectomy resulted in a significant decrease in blood pressure in 80.3% of patients within 2-7 days postoperatively, with 39.7% requiring no antihypertensive therapy at 1 year.
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