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December 1, 1987Journal of Clinical InvestigationOpen Access

Abnormal ultraviolet mutagenic spectrum in plasmid DNA replicated in cultured fibroblasts from a patient with the skin cancer-prone disease, xeroderma pigmentosum.

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Authors

SSSaraswathy SeetharamCenter for Biologics Evaluation and ResearchMPMiroslava Protić‐SabljićNational Institutes of HealthMSMichael M. SeidmanNational Institutes of Health

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Cite This Study

Seetharam et al. (1987) studied this question.

synapsesocial.com/papers/6aaa21ac5e1c2e91a8fbccaehttps://doi.org/10.1172/jci113248
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Photoreversal: dependent release of thymidine and thymidine monophosphate from pyrimidine dimer containing DNA excision fragments isolated from ultraviolet-damaged human fibroblasts1986 · 48 citations
  2. 2Kinds of mutations formed when a shuttle vector containing adducts of (+/-)-7 beta, 8 alpha-dihydroxy-9 alpha, 10 alpha-epoxy-7,8,9, 10-tetrahydrobenzo[a]pyrene replicates in human cells.1987 · 98 citations
  3. 3Sequence specificity of point mutations induced during passage of a UV-irradiated shuttle vector plasmid in monkey cells.1986 · 168 citations
  4. 4One pyrimidine dimer inactivates expression of a transfected gene in xeroderma pigmentosum cells.1985 · 191 citations