Elevation of B-type natriuretic peptide levels in acute respiratory distress syndrome
Key result
Parapneumonic ARDS presents with peak BNP >1300 pg/mL despite normal LV function.
- n=1
Why the study?
Less is known about B-type natriuretic peptide levels in patients with acute respiratory distress syndrome.
Comparison
Mechanical ventilation and inhalation of nitric oxide
Design
Case report
Follow-up
3 weeks
Authors
Discussion
Loading...
Member takes
Implication
BNP elevation in ARDS without LV dysfunction warrants interpretive caution; leaves open BNP specificity in non-cardiac respiratory failure.
Study Design
Type
Case Report (n=1)
Structured PICO
P
Population
A 27-year-old man with parapneumonic ARDS and an extraordinarily increased BNP level.
E
Exposure
Mechanical ventilation and inhalation of nitric oxide
O
Outcome
B-type natriuretic peptide (BNP) levelssurrogate
BNP can be markedly elevated in ARDS patients without left ventricular dysfunction, likely reflecting right ventricular overload from increased pulmonary vascular resistance.
Cite This Study
Maeder et al. (2003) conducted a case report in Acute respiratory distress syndrome (ARDS) (n=1). Parapneumonic ARDS was evaluated on B-type natriuretic peptide (BNP) level. A 27-year-old man with parapneumonic ARDS exhibited impressively high peak BNP levels (>1300 pg/mL) in the absence of left ventricular dysfunction, which decreased to 113 pg/mL with respiratory improvement.