Why the study?
Risk factors associated with type 2 diabetes in young adults aged 18 to 29 years were characterized to develop a noninvasive risk assessment tool for younger American populations.
Can a noninvasive risk assessment tool accurately predict the 5-year risk of developing prediabetes or diabetes in young American Indian adults?
Population
590 young American Indian adults aged 18 to 29 years with normoglycemia
Comparison
Noninvasive risk assessment tool using parental history, obesity, alcohol, fasting glucose
Design
Cohort study using Strong Heart Family Study data
Follow-up
5 years
Key result
A noninvasive risk assessment tool using parental history, obesity, alcohol, and fasting glucose predicted the 5-year onset of prediabetes or diabetes in young American Indians with an AUC of 0.68.
Authors
Loading...
May inform early risk stratification in young American Indians; leaves open external validation before clinical use.
Cohort (n=590)
Can a noninvasive risk assessment tool accurately predict the 5-year risk of developing prediabetes or diabetes in young American Indian adults?
Effect estimate: AUC 0.68
A noninvasive self-assessment tool using basic clinical and lifestyle factors provides reasonably good discrimination for predicting early-onset diabetes risk in young American Indian adults.
Yan et al. (2016) conducted a cohort in Type 2 diabetes risk (n=590). Risk factors (parental history of diabetes, obesity, alcohol consumption, high fasting glucose) was evaluated on Onset of prediabetes/diabetes in 5 years (AUC 0.68). A noninvasive risk assessment tool using parental history, obesity, alcohol, and fasting glucose predicted the 5-year onset of prediabetes or diabetes in young American Indians with an AUC of 0.68.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: