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April 29, 2010Diabetes/Metabolism Research and Reviews

Incidence rates and predictors of diabetes in those with prediabetes: the Strong Heart Study

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Why the study?

Does prediabetes predict incident type 2 diabetes in American Indians?

Population

1677 American Indians who were nondiabetic at baseline

Comparison

Prediabetes vs Normal glucose tolerance (NGT) at baseline

Design

Cohort

Follow-up

median 7.8 years

Authors

HWHong WangChengdu University of Information TechnologyNSNawar SharaMedStar Washington Hospital CenterDCDarren CalhounCalhoun Community College

Discussion

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Member takes

Overview

Supports monitoring prediabetic American Indians; leaves open whether targeting obesity alters progression.

Structured PICO

Does prediabetes predict incident type 2 diabetes in American Indians?

P
Population
1677 American Indians who were nondiabetic at baseline
I
Intervention
Prediabetes (impaired glucose tolerance and/or impaired fasting glucose according to ADA 2003 criteria)
C
Comparator
Normal glucose tolerance (NGT) at baseline
O
Outcome
Incident type 2 diabeteshard clinical

Prediabetes is a strong independent predictor of conversion to type 2 diabetes in American Indians, with obesity and insulin resistance being key modifiable risk factors.

Cite This Study

Wang et al. (2010) studied this question.

synapsesocial.com/papers/6a1d2d78ba65f5ee325df291https://doi.org/10.1002/dmrr.1089
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