Key result
IV hydrocortisone and levothyroxine resolve central neurogenic hyperventilation and cognitive impairment in myxedema coma.
Why the study?
Central neurogenic hyperventilation is a rare syndrome characterized by respiratory alkalosis without pulmonary disorder, requiring further clinical description.
Case Report (n=1)
No
Answers are grounded in this paper and cite their sources.
Hypothyroidism coma can present as central neurogenic hyperventilation in critically ill postoperative patients and responds to thyroid hormone replacement.
The main causes of hyperventilation are: pulmonary embolism, severe asthma attack, pneumothorax, myocardial ischemia, congestive heart failure, hyperthyroidism, pheochromocytoma, alcohol and drugs, severe metabolic acidosis, fever, acute pain, ischemia and traumatism. Even if most of CNH are caused by CNS tumours, especially lymphomas, invasion of brain tissue may produce tissue acidosis and develop hyperventilation.
No takes yet. Share an insight, caveat, or question.
A 2016 study conducted a case report in Central Neurogenic Hyperventilation secondary to Hypothyroidism Coma (n=1). IV Hydrocortisone and IV levothyroxine was evaluated on Resolution of symptoms. Administration of IV hydrocortisone and levothyroxine resolved central neurogenic hyperventilation and cognitive impairment in a patient with postoperative hypothyroidism coma.
Synapse has enriched 10 related papers. Consider them for comparative context: