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Pyoderma gangrenosum is a rare, inflammatory, neutrophilic dermatosis that is a diagnosis of exclusion. We present a unique case of recalcitrant pyoderma gangrenosum attributable to levamisole-adulterated cocaine with variable, nonsustained responses to several systemic immunosuppressants and ultimate remission with oral tofacitinib.
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Choi et al. (2020) studied this question.
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