Synthesis of some new indole derivatives containing pyrazoles with potential antitumor activity

A series of new [1-(4-methoxybenzyl)indol-3-yl](1H-pyrazol-1-yl)methanones, 1-(1-(4methoxybenzyl)-1H-indole-3-carbonyl)-3-subsituted-1H-pyrazol-5(4H)-ones have been developed using the 1-(4-methoxybenzyl)-1H-indole-3-carbohydrazide 1 as a key intermediate.The target compounds were tested in-vitro for tumor cell-growth inhibition.