Key result
Prior MI linked to ~82% higher serum catestatin levels in ADHF patients.
Why the study?
The role of catestatin in acutely decompensated heart failure and myocardial infarction was poorly elucidated, despite its implicated role in regulating neurohumoral activity.
Comparison
Stratified by MI history and LVEF
Design
Observational study
Authors
Loading...
CST elevation in ADHF with prior MI associates with NYHA class; leaves open its prognostic role pending prospective studies.
Cross-Sectional (n=90)
No
Absolute Event Rate: 8.94% vs 4.9%
p-value: p=0.001
Catestatin levels are elevated in ADHF patients with a history of MI and correlate with advanced symptomatic burden despite a favorable cardiometabolic profile.
Borovac et al. (2019) conducted a cross-sectional in Acutely decompensated heart failure (n=90). History of myocardial infarction vs. No history of myocardial infarction was evaluated on Catestatin serum levels (ng/mL) (p=0.001). Acutely decompensated heart failure patients with a history of myocardial infarction had significantly higher serum catestatin levels compared to those without (8.94 vs. 4.90 ng/mL).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: