Key result
Atypical antipsychotics during pregnancy linked to a ~38% instrumental delivery rate, gestational diabetes, and prematurity.
Why the study?
Limited data exist about the use of atypical antipsychotic agents in pregnancy despite many women suffering from psychosis in their childbearing years.
What are the pregnancy outcomes for women prescribed atypical antipsychotic agents during pregnancy?
Observational (n=45)
No
What are the pregnancy outcomes for women prescribed atypical antipsychotic agents during pregnancy?
Atypical antipsychotic use during pregnancy in this small cohort was associated with elevated instrumental delivery rates and gestational diabetes, while major malformations were similar to baseline community rates.
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Provides real-world pregnancy outcome data; leaves open questions on fetal safety requiring prospective confirmation.
Friedman et al. (2016) conducted an observational in Mental health disorders in pregnancy (n=45). Atypical antipsychotic agents was evaluated on Pregnancy outcomes (instrumental delivery, gestational diabetes, prematurity, malformations). Atypical antipsychotic use during pregnancy in 45 women resulted in a 38% instrumental delivery rate, 13% gestational diabetes rate, and 7% prematurity rate.
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