Key result
Combining modified frailty and prognostic nutritional indices predicts postoperative hip fracture complications with AUC ~0.79.
Why the study?
There is no consensus on the best risk assessment technique for predicting complications after hip surgery in the elderly, hindering accurate surgical risk assessment.
Does a risk assessment model combining 5-mFI and PNI predict postoperative complications in elderly patients undergoing hip fracture surgery?
Observational (n=150)
Does a risk assessment model combining 5-mFI and PNI predict postoperative complications in elderly patients undergoing hip fracture surgery?
Effect estimate: AUC 0.788 (95% CI 0.715-0.860)
p-value: p=<0.01
A multivariable evaluation model including 5-mFI and PNI shows high predictive value for adverse outcomes in elderly patients undergoing hip fracture surgery.
Combined 5-mFI/PNI model may aid preoperative risk stratification in elderly hip fracture patients; leaves open prospective validation before clinical adoption.
Aim: There is currently no consensus on the best risk assessment technique for predicting complications after hip surgery in the elderly, which is hindering the accuracy of surgical risk assessment. The goal of this study was to build a risk assessment model and evaluate its predictive value using the modified frailty index (5-mFI) and the prognostic nutritional index (PNI).Methods: A retrospective investigation was undertaken on 150 patients (aged ≥60 years) who had hip fracture surgery. Using univariate and multivariate logistic regression models, the relationship between combined 5-mFI and PNI and the evaluation of postoperative unfavorable outcomes such as infection and unscheduled intensive care unit (ICU) admission was investigated. Finally, utilizing receiver operating characteristic (ROC) curve analysis, the model’s predictive value for adverse outcomes following hip fracture surgery in elderly patients was assessed.Results: Univariate and multivariate logistic analyses revealed that preoperative PNI, 5-mFI, ASA, and gender acted as independent predictors of adverse outcomes after hip fracture surgery in the elderly. According to the ROC curve analysis, the predictive model demonstrated a high predictive value for total postoperative complications (AUC: 0.788; 95%CI: 0.715–0.860; p<0.01), infectious complications (AUC: 0.798; 95% CI: 0.727–0.868; P<0.001), and unplanned ICU admission (AUC: 0.783; 95% CI: 0.705–0.861; P<0.001).Conclusions: The multivariable evaluation model, which included 5-mFI and PNI, showed a high predictive value and can hence be applied to predict the adverse outcomes in elderly patients undergoing hip fracture surgery.
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Zhou et al. (2022) conducted an observational in Hip fracture surgery (n=150). Combined modified frailty index (5-mFI) and prognostic nutritional index (PNI) was evaluated on Total postoperative complications (AUC 0.788, 95% CI 0.715-0.860, p=<0.01). A predictive model combining the modified frailty index and prognostic nutritional index accurately predicted total postoperative complications after hip fracture surgery (AUC 0.788; 95% CI 0.715-0.860).
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