Key result
Higher geriatric nutritional risk index linked to ~18% lower postoperative mortality.
Why the study?
It is currently difficult to accurately predict postoperative prognosis for older patients with hip fractures.
Does a lower geriatric nutritional risk index predict postoperative mortality and complications in older patients with hip fracture?
Meta-Analysis (n=3,959)
Does a lower geriatric nutritional risk index predict postoperative mortality and complications in older patients with hip fracture?
Hazard Ratio: 0.82 (95% CI 0.72–0.92)
p-value: p=.001
The geriatric nutritional risk index (GNRI) is a useful prognostic indicator for older patients undergoing hip fracture surgery, with lower scores predicting higher mortality and complication rates.
GNRI may refine preoperative mortality risk stratification in older hip fracture patients; supports its prognostic role but leaves open whether interventions improve outcomes.
BACKGROUND: Hip fracture is common in elderly individuals and is accompanied by a relatively high mortality rate. However, it is currently difficult to accurately predict postoperative prognosis for older patients with hip fractures. The aim of this meta-analysis was to further determine the prognostic value of the geriatric nutritional risk index (GNRI) for patients who underwent hip fracture surgery. METHODS: The Medline, EMBASE, Web of Science, and CNKI databases were searched up to September 19, 2023, for available studies. The primary and secondary outcomes were the mortality and complication rates, respectively. Hazard ratios (HRs) and relative risks with corresponding 95% confidence intervals (CIs) were separately combined to assess the associations between the GNRI and mortality and complication rates. All the statistical analyses were performed with STATA 15.0 and SPSS 22.0 software. RESULTS: A total of 9 studies with 3959 patients were included. The pooled results demonstrated that a lower GNRI was significantly related to an increased risk of postoperative mortality (HR = 0.82, 95% CI = 0.72-0.92, P = .001). In addition, the GNRI predicted the risk of overall postoperative complications (52% vs 35.5%, P = .04) and pneumonia (33.3% vs 13.6%, P = .010). CONCLUSION: The GNRI might serve as a novel prognostic indicator for older patients with hip fractures, and a lower GNRI indicates an increased risk of postoperative mortality and complication rates.
No takes yet. Share an insight, caveat, or question.
Xiu Liu (2024) conducted a meta-analysis in hip fracture (n=3,959). Lower geriatric nutritional risk index (GNRI) vs. Higher GNRI was evaluated on postoperative mortality (HR 0.82, 95% CI 0.72-0.92, p=.001). A lower geriatric nutritional risk index was significantly associated with an increased risk of postoperative mortality (HR 0.82; 95% CI 0.72-0.92; P=.001).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: