Key result
Type 2 diabetes linked to ~49% lower FVC versus healthy controls.
Why the study?
Less is known about the effect of diabetes mellitus on pulmonary function in type 2 DM patients.
Does Type 2 Diabetes Mellitus reduce pulmonary function parameters in patients compared to healthy controls?
Case-Control (n=60)
No
Does Type 2 Diabetes Mellitus reduce pulmonary function parameters in patients compared to healthy controls?
Absolute Event Rate: 1.44% vs 2.81%
p-value: p=0.001
Type 2 diabetes mellitus is associated with significantly impaired lung function independent of smoking.
Background: Diabetes Mellitus (DM) is a metabolic disorder precipitating micro-vascular, macrovascular complications and peripheral vascular disease.Less has been known about the after effect of diabetes on lungs.So this work was carried out to know the effect of diabetes mellitus on pulmonary functions.Objective: To find out the effect of diabetes mellitus on pulmonary functions in type 2 DM Material and method: A case-control study was conducted on 30 type 2 DM patients and age sex matched 30 controls after screening both the groups for smoking and acute/chronic pulmonary disease.All subjects underwent screening with detailed history, anthropometry and spirometry at Department of Physiology, SMS medical college, Jaipur.Significance of difference of pulmonary parameters in both the groups was inferred with unpaired't' Test.Result: Diabetic patients showed highly significant (P<0.001)reduction in almost all the pulmonary parameters.The reduction in pulmonary parameters was not associated with severity and duration of disease.Conclusion: Diabetic patients showed impaired lung function independent of smoking.Although it was not associated with severity but duration of DM affect FVC and FEV 1 .
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Anuradha Yadav (2013) conducted a case-control in Type 2 Diabetes Mellitus (n=60). Type 2 Diabetes Mellitus vs. Age and sex matched healthy controls was evaluated on Forced Vital Capacity (FVC) (p=0.001). Type 2 diabetes mellitus was associated with significantly reduced pulmonary function, including a lower Forced Vital Capacity (1.44 vs 2.81, p=0.001) compared to healthy controls.
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